Winds of Change: Adobe Air

While I don't think that the tagline of "Banish Your Browser" is quite accurate at this point, the tools described on this PCWorld article are quite useful if you want to get more functionality out of Web 2.0.  The only deterrent for some folks might be that you have to download and install these applications.  I think DeskTube, DestroyFlickr, TweetDeck, Snackr and Nomee seem to be the most likely candidates to show to customers that have their own computers.  I don't think any of these programs will appeal to folks that lack the hardware and a regular connection source.